Hydroxyamate-containing materials for the inhibition of...

Details Hydroxyamate-containing materials for the inhibition of... Hydroxyamate-containing materials for the inhibition of...

A - Human Necessities

61

K

A61K 31/785 (2006.01) A61L 15/44 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) C08F 8/30 (2006.01) C08F 8/32 (2006.01) C08F 220/14 (2006.01) C08F 220/58 (2006.01)

Patent

CA 2572597

Therapeutic polymers containing hydroxamate group that binds and thus inhibits zinc containing enzymes such as matrix metalloproteinases. The implantation fo such material inhibits remodeling in its vicinity.

L'invention concerne des polymères thérapeutiques contenant un groupe hydroxamate qui se lie et donc inhibe des enzymes contenant du zinc, telles que des métalloprotéinases matricielles. L'implantation de ces matériaux permet d'inhiber un remodelage à proximité de ceux-ci.

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