Biopolymer foams having extracellular matrix particulates

Details Biopolymer foams having extracellular matrix particulates Biopolymer foams having extracellular matrix particulates

C - Chemistry, Metallurgy

08

J

C08J 9/28 (2006.01) A61L 27/00 (2006.01)

Patent

CA 2205446

A biopolymer solution is polymerized to form a gel which is freeze-dried and crosslinked with ultraviolet radiation to form a biopolymer foam. The foam is filled with a collagen solution and the combination is freeze-dried or the foam is filled with a collagen solution containing extracellular matrix particulates and that combination is freeze-dried, thereby forming a foam to which extracellular matrix particulates are attached.

Une solution biopolymère est polymérisée pour former un gel qui est lyophilisé et réticulé à l'aide d'un rayonnement ultraviolet de façon à former une mousse biopolymère. La mousse est remplie d'une solution de collagène et la combinaison ainsi obtenue est lyophilisée, ou la mousse est remplie d'une solution de collagène contenant des matières particulaires de matrice extracellulaire et cette combinaison est lyophilisée de manière à former une mousse à laquelle sont attachées les matières particulaires en matrice extracellulaire.

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