Topical ophthalmic mast cell stabilizers for treating...

Details Topical ophthalmic mast cell stabilizers for treating... Topical ophthalmic mast cell stabilizers for treating...

A - Human Necessities

61

K

A61K 45/00 (2006.01) A61P 27/14 (2006.01) G01N 33/15 (2006.01)

Patent

CA 2374002

Topical ophthalmic anti-allergy drugs are identified by the extent of their interaction with a phospholipid model membrane. Disclosed are topically administrable ophthalmic formulations containing amphipathic anti-allergy compounds at concentrations such that the drugs have Surface Activity Ratings from about 2-11. Provided the drug is not selected from the group consisting of olopatadine; ketotifen; emedastine; pheniramine; pyrilamine; cromolyn; nedocromil; and levocabastine.

Cette invention a permis d'identifier des médicaments anti-allergiques ophtalmiques topiques grâce à l'étendue de leur interaction avec une membrane modèle de phospholipides. Cette invention concerne des formulations ophtalmiques à administration topique, contenant des composés anti-allergiques amphipathiques à des concentrations telles que ces médicaments présentent des indices d'activité de surface compris entre environ 2 et 11.

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