Pyrrolidine and thiazole derivatives with...

C - Chemistry – Metallurgy – 07 – D

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C07D 277/06 (2006.01) A61K 31/425 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2285446

A method of treatment of bacterial infections in humans or animals which comprises administering, in combination with a .beta.-lactam antibiotic, a therapeutically effective amount of an amino acid derivative or a pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof.

Méthode de traitement d'infections bactériennes chez les humains et les animaux consiste à administrer, en association avec une .beta.-lactamine, une quantité thérapeutiquement efficace d'un dérivé d'acide aminé ou un sel pharmaceutiquement acceptable, un solvate ou un ester hydrolysable in vivo de ce dernier.

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