Lentiviral vector-mediated gene transfer and uses thereof

Details Lentiviral vector-mediated gene transfer and uses thereof Lentiviral vector-mediated gene transfer and uses thereof

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 35/00 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2432301

The present invention provides a means of human gene therapy for inherited or acquired proliferative ocular disease. It furnishes methods to exploit the ability of lentiviral vectors to transduce both mitotically active and inactive cells so that eye diseases may be treated.

La présente invention traite d'un moyen pour traiter par thérapie génique les maladies ophtalmologiques prolifératives acquises ou héréditaires. L'invention a pour objet des procédés pour exploiter la capacité des vecteurs lentiviraux à transduire des cellules actives et inactives d'un point de vue mitotique ce qui permet de soigner ces maladies.

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