Antibodies against a proliferating inducing ligand (april)

Details Antibodies against a proliferating inducing ligand (april) Antibodies against a proliferating inducing ligand (april)

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2754127

The present invention relates to a binding com-pound which binds to human APRIL. More specifically the in-vention provides, compositions of anti-APRIL specific anti-bodies and methods to use such antibodies in modulating the biological activity APRIL, particularly in inflammatory dis-eases, inhibition of cell proliferation and cancer.

La présente invention concerne un composé de liaison qui se lie à APRIL humain. Plus précisément, l'invention porte sur des compositions d'anticorps spécifiques anti-APRIL et sur des procédés d'utilisation de tels anticorps dans la modulation de l'activité biologique APRIL, en particulier dans des maladies inflammatoires, l'inhibition d'une prolifération cellulaire et du cancer.

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