Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol...

Details Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol... Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 45/06 (2006.01) C07D 211/46 (2006.01)

Patent

CA 2319713

Provided are methods and compositions for treating hepatitis virus infections in mammals, especially humans. The methods comprise (1) administering N- substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, mixtures thereof, or immunomodulating/immunostimulating agents, or (2) administering N- substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, or mixtures thereof, and immunomodulating/immunostimulating agents.

L'invention porte sur des procédés et des compositions utilisés dans le traitement des infections dues au virus de l'hépatite chez des mamifères, notamment chez l'homme. Ces procédés consistent à (1) administrer des composés N-substitué-1,5-didésoxy-1,5-imino-D-glucidol, seuls, ou en combinaison avec des agents antiviraux nucléosidiques, des agents antiviraux nucléotidiques, des mélanges de ceux-ci ou des agents immunomodulateurs/immunostimulateurs, ou (2) administrer des composés N-substitué-1,5-didésoxy-1,5-imino-D-glucidol, seuls, ou en combinaison avec des agents antiviraux nucléosidiques, des agents antiviraux nucléotidiques, des mélanges de ceux-ci et des agents immunomodulateurs/immunostimulateurs

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