Antimicrobial therapy for bacterial infections

Details Antimicrobial therapy for bacterial infections Antimicrobial therapy for bacterial infections

A - Human Necessities

61

K

A61K 31/195 (2006.01) A61K 31/138 (2006.01)

Patent

CA 2606289

The disclosure provides a molecular genetic approach of targeted mutagenesis and heterologous expression, coupled with in vitro and in vivo models of bacterial pathogenesis, to demonstrate that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.

L'invention concerne une technique de génétique moléculaire de mutagénèse ciblée et d'expression hétérologue, en association avec des modèles in vitro et in vivo de pathogénèse bactérienne, permettant de démontrer que le pigment de S. aureus est un facteur de virulence et une nouvelle cible potentielle pour un traitement antimicrobien.

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