C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/18 (2006.01) A61K 31/40 (2006.01) A61K 31/58 (2006.01) A61P 25/28 (2006.01) C12P 33/20 (2006.01)
Patent
CA 2181371
The present invention relates to compounds of formula (I) and the pharmaceutically acceptable salts thereof which are useful as potassium channel antagonists, particularly Maxi-K channel antagonists, and thus useful in treating Alzheimer's Disease and other cognitive disorders. This invention is also related to a method of making the compound of formula (I).
La présente invention concerne des composés de la formule (I) et des sels pharmaceutiquement acceptables de ces composés, qui sont utiles en tant qu'antagonistes des vannes à potassium, en particulier en tant qu'antagonistes des vannes Maxi-K, et qui peuvent donc être utilisés pour traiter la maladie d'Alzheimer et d'autres troubles cognitifs. Cette invention concerne aussi un procédé de préparation desdits composés de formule (I).
Garcia Maria L.
Giacobbe Robert A.
Hensens Otto D.
Lee Seok H.
Mcmanus Owen B.
Goudreau Gage Dubuc
Merck & Co. Inc.
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