Imidazolidyl macrolides

Details Imidazolidyl macrolides Imidazolidyl macrolides

C - Chemistry, Metallurgy

07

H

C07H 19/01 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2116674

Imidazolidyl macrolides of general structural formula (I) have been prepared from suitable precursors by alkylation and/ or arylation at C-3" and/or C-4" of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases; infectious diseases, the prevention of rejection of foreign organ transplants and/or re- lated afflictions, diseases and illnesses.

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