Prevention and treatment of skeletal disorder with ep2...

Details Prevention and treatment of skeletal disorder with ep2... Prevention and treatment of skeletal disorder with ep2...

A - Human Necessities

61

K

A61K 31/18 (2006.01) A61K 31/00 (2006.01) A61K 31/192 (2006.01) A61K 31/195 (2006.01) A61K 31/197 (2006.01) A61K 31/20 (2006.01) A61K 31/381 (2006.01) A61K 31/41 (2006.01)

Patent

CA 2275595

Methods for treating (e.g. preventing bone loss) a mammal having a condition which presents with low bone mass or other skeletal disorders for promoting fracture healing comprising inhibiting the EP2 receptor subtype by administering to a mammal a therapeutically effective amount of an EP2 receptor subtype agonist.

L'invention concerne des procédés permettant de traiter (par exemple pour prévenir la perte osseuse) un mammifère souffrant d'un état associé à une faible masse osseuse ou à d'autres affections osseuses, pour favoriser la guérison d'une fracture, ces procédés consistant à inhiber le sous-type de récepteur EP2 par administration audit mammifère d'une dose thérapeutiquement efficace d'un agoniste du sous-type de récepteur EP2.

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