C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/06 (2006.01) A61K 31/445 (2006.01) A61K 31/4525 (2006.01) A61K 31/4535 (2006.01) A61K 31/454 (2006.01) C07D 211/70 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2510400
Compounds of general formula: wherein R1, R2, R3, R4, and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
L'invention se rapporte à des composés de formule générale (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ sont tels que définis dans la description, à des sels et des énantiomères de ces composés, ainsi qu'à des compositions pharmaceutiques contenant lesdits composés. Les composés selon l'invention peuvent être utilisés à des fins thérapeutiques, en particulier pour soulager la douleur.
Brown William
Griffin Andrew
Walpole Christopher
Astrazeneca Ab
Mccarthy Tetrault Llp
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