C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/71 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 37/04 (2006.01) A61P 37/06 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 14/16 (2006.01) C07K 14/525 (2006.01) C07K 14/545 (2006.01) C07K 16/00 (2006.01) C07K 16/10 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12N 9/64 (2006.01)
Patent
CA 2324340
Covalently reactive antigen analogs are disclosed herein. The antigens of the invention may be used to stimulate production of catalytic antibodies specific for predetermined antigens associated with particular medical disorders. The antigen analogs may also be used to permanently inactivate endogenously produced catalytic antibodies produced in certain autoimmune diseases as well as in certain lymphoproliferative disorders.
L'invention concerne des analogues antigéniques réactifs par covalence, ces antigènes pouvant être utilisés pour stimuler la production d'anticorps catalytiques spécifiques à des antigènes prédéterminés, associés à des dysfonctionnements médicaux définis. Ces analogues antigéniques peuvent également être utilisés pour inactiver de manière permanente des anticorps catalytiques endogènes, produits au cours de certaines maladies auto-immunes et de certaines affections lymphoprolifératives.
Gololobov Gennady
Paul Sudhir
Smith Larry
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Smith Larry
University Of Nebraska Board Of Regents
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