A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2570998
The invention described herein relates to improved strategies for designing and practicing treatments and clinical trials based upon active immunotherapy protocols, particularly by making diagnostic use of portions of the therapeutic regimen and adjusting the course of treatment if necessary. Embodiments of the invention include methods for determining a course of treatment and methods for treating a patient in which responsiveness to a non- final step of a multi-step active immunotherapy protocol is assessed to determine if, how and when to continue treatment, progress to a different stage of treatment, or discontinue treatment.
L'invention concerne des stratégies améliorées de conception et de mise en oeuvre de traitements et d'essais cliniques conformément à des protocoles d'immunothérapie active, comprenant en particulier l'utilisation de diagnostics dans certaines parties du schéma de traitement, et la modification du déroulement du traitement si nécessaire. Différents modes de mise en oeuvre décrits comprennent des méthodes permettant de déterminer le déroulement d'un traitement, et des méthodes de traitement, au cours desquelles évalue la réponse à une étape autre que l'étape finale d'un protocole d'immunothérapie active comportant des étapes multiples, afin de déterminer l'opportunité, le mode, et la planification de la poursuite du traitement, du passage à un stade de traitement différent, ou de l'interruption du traitement.
Bot Adrian
Diamond David C.
Mannkind Corporation
Perry + Currier
LandOfFree
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