Substituted pyrimidines for the treatment of cancer

Details Substituted pyrimidines for the treatment of cancer Substituted pyrimidines for the treatment of cancer

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2755759

The present invention encompass-es compounds of general formula (1) wherein B, R1 to R5, R x, m and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell pro-liferation, and their use in such treatment.

La présente invention porte sur des composés représentés par la formule générale (1), dans laquelle B, R1 à R5, Rx, m et n sont tels que définis dans la revendication 1, lesquels sont appropriés pour le traitement de maladies caractérisées par une prolifération cellulaire excessive ou anormale. L'invention porte également sur l'utilisation de ces composés dans un tel traitement.

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