Megsin protein

Details Megsin protein Megsin protein

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2303762

A gene expressed specifically in mesangial cells. A DNA expressed specifically in mesangial cells; a protein encoded by this DNA; an antibody binding to this protein, etc. These substances are indigenous to mesangial cells and, therefore, useful in, for example, identifying mesangial cells and detecting abnormalities in mesangial cells. Moreover, it is expected that the function of the above protein would contribute to the clarification of the functions of mesangial cells and, in its turn, to the clarification of the causes of diseases relating to mesangial cells. This protein is also expected to be applicable to the treatment, diagnosis, etc. of diseases relating to mesangial cells.

L'invention concerne un gène exprimé spécifiquement dans les cellules mésangiales, de l'ADN lui aussi exprimé spécifiquement dans ces cellules, une protéine codée par cet ADN, un anticorps se liant sur ladite protéine, etc. Etant propres aux cellules mésangiales, les substances en question sont utiles, par exemple, pour identifier ces cellules et détecter leurs anomalies. De plus, il est probable que la fonction de la protéine susmentionnée contribue à clarifier les fonctions des cellules mésangiales et, partant, à élucider les causes de maladies affectant lesdites cellules. En outre, il est probable que la protéine considérée soit utilisable, entre autres, pour le traitement et le diagnostic des maladies qui affectent les cellules mésangiales.

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