Nucleic acid and corresponding protein entitled 98p4b6...

Details Nucleic acid and corresponding protein entitled 98p4b6... Nucleic acid and corresponding protein entitled 98p4b6...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) C07K 16/30 (2006.01) C07K 16/32 (2006.01) C12N 5/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2496566

A novel gene 98P4B6 (also designated STEAP-2) and its encoded protein, and variants thereof, are described wherein 98P4B6 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 98P4B6 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 98P4B6 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 98P4B6 can be used in active or passive immunization.

L'invention concerne un nouveau gène 098P4B6 (également dénommé STEAP-2) et la protéine codée par ce gène, ainsi que des variants de celle-ci. 98P4B6 présente une expression spécifique du tissu dans le tissu normal adulte, et il est exprimé de manière aberrante dans les cancers énumérés dans la table I. 98P4B6 offre par conséquent une cible diagnostique, pronostique, préventive et/ou thérapeutique pour le cancer. Le gène 98P4B6 ou un fragment de celui-ci, la protéine correspondante ou les variants ou un fragments de celle-ci peuvent être utilisés pour susciter une réponse immunitaire humorale ou cellulaire. Les anticorps ou les lymphocytes T réagissant avec 98P4B6 peuvent être utilisés pour l'immunisation active ou passive.

Affiliated with

Also associated with

Rating

Nucleic acid and corresponding protein entitled 98p4b6... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acid and corresponding protein entitled 98p4b6..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid and corresponding protein entitled 98p4b6... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1986831