C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/48 (2006.01) A61K 31/47 (2006.01) A61K 38/04 (2006.01) C07D 215/20 (2006.01) C07D 215/60 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07K 5/04 (2006.01) C07K 5/078 (2006.01) C07K 7/06 (2006.01)
Patent
CA 2186717
Substituted quinoline-2-carboxamides, their preparation and their use as pharmaceuticals, and intermediates The invention relates to substituted quinoline-2- carboxylic acid amides of the formula I Image (I) , their preparation and their use, and intermediates which are formed in the preparation of the compounds of the formula I. The compounds according to the invention are used as inhibitors of prolyl 4-hydroxylase and as pharmaceuticals (medicaments) for treatment of fibrotic diseases.
Baringhaus Karl-Heinz
Bickel Martin
Tschank Georg
Weidmann Klaus
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Fibrogen Inc.
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