Preventing rejection of transplanted tissue using regulatory...

Details Preventing rejection of transplanted tissue using regulatory... Preventing rejection of transplanted tissue using regulatory...

A - Human Necessities

61

K

A61K 35/12 (2006.01)

Patent

CA 2601398

Methods of preventing rejection of transplanted tissue. Recipient alloactivated regulatory T cells generated ex vivo are introduced into the recipient before transplantation. Donor antigen is introduced into the recipient after transplantation to boost recipient regulatory T cells.

L'invention concerne des procédés permettant de prévenir le rejet de tissus transplantés. Des lymphocytes T régulateurs de receveur alloactivés générés in vivo sont introduits chez le receveur avant transplantation. L'antigène donneur est introduit chez le receveur après transplantation afin d'amplifier les lymphocytes T régulateurs.

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