Transdermal therapeutic system suitable for heat application...

A - Human Necessities – 61 – K

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Details

A61K 9/70 (2006.01) A61K 31/4468 (2006.01) A61K 47/34 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2513402

The invention relates to a transdermal therapeutic system (TTS) comprising at least one pharmacological active substance, which is suitable for heating up to a temperature above skin temperature, thereby promoting the permeation rate of the active substance. The transdermal therapeutic system comprises at least one layer containing the active substance and one peelable backing layer, and is characterized in that the layer containing the active substance mainly consists of a polysiloxane in which the active substance is partially dissolved.

L'invention concerne un système thérapeutique transdermique (TTS) contenant au moins une substance pharmaceutique active, ce système étant apte à réchauffer à une température supérieure à celle de la peau, afin d'augmenter la vitesse de perméation de la substance active. Le système comporte au moins une couche dorsale imperméable à la substance active, au moins une couche contenant la substance active et une couche pelable. L'invention est caractérisée en ce que la couche contenant la substance active est composée essentiellement d'un polysiloxane, la substance active étant partiellement à l'état soluble.

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