Novel piperidine derivatives with paf antagonist activity

Details Novel piperidine derivatives with paf antagonist activity Novel piperidine derivatives with paf antagonist activity

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2180660

Compounds of general formula (I) and their salts and solvates are PAF antagonists and as such are useful in the treatment of various diseases or disorders mediated by PAF. Pharmaceutical compositions including these compounds and processes for their preparation are also provided.

La présente invention concerne des composés de la formule générale (1) ainsi que leurs sels et solvats. Ce sont des antagonistes du facteur PAF, et en tant que tels, ils sont particulièrement adapté au traitement de diverses affections et de divers troubles liés au facteur PAF. L'invention concerne également des compositions pharmaceutiques incluant ces composés. L'invention concerne enfin des procédés de préparation de ces composés.

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