C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/02 (2006.01) A61K 31/47 (2006.01) A61K 35/14 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61L 2/00 (2006.01) A61L 2/10 (2006.01) A61M 1/36 (2006.01) C07D 221/14 (2006.01) C07K 2/00 (2006.01) C09B 57/08 (2006.01) C12N 7/04 (2006.01) A61L 25/00 (1990.01)
Patent
CA 2130828
A class of predominantly hydrophobic monomeric or dimeric non-azo N-substituted 1,8-naphthalimide compounds, each bearing, at its 3-position, a nucleofuge and, at its 4-position, a heteroatomic electron-releasing group. A preferred embodiment is a "monomeric" non-azo N- substituted-l,8-naphthalimide compound bearing, at a 3- position, a nucleofuge and, at a 4-position, a heteroatomic electron-releasing group, which is being characterized as having a heteroatom directly linked to the 4-position and having at least one hydrogen directly attached to the heteroatom. An additional embodiment is a predominantly hydrophobic "dimeric" non-azo bis-naphthalimide compound, having at least two 1,8-naphthalimide moieties each bearing, at a 3-positon, a nucleofuge and, at a 4-position, a heteroatomic electron-releasing group which is being characterized as having a heteroatom directly linked to the 4-position and having at least one hydrogen directly attached to the heteroatom. The bis-naphthalimide compound is further characterized as giving an activated derivative after being activated by a sufficient amount of activating agent in an environment independent of the presence or absence of oxygen. The activated species initiate chemical changes in lipid bilayer membranes of viruses and other target cells. These changes can eradicate viruses and other target cells. The activated species can also cause structural changes in lipid and any associated proteins and polypeptides at a level beneath the surface of the membrane, leading to polymerization and crosslinking.
Judy Millard M.
Lewis David E.
Matthews J. Lester
Utecht Ronald E.
Kirby Eades Gale Baker
Microbiomed Corporation
Photobiomed
LandOfFree
Non-azo naphthalimide dyes and uses for same does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-azo naphthalimide dyes and uses for same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-azo naphthalimide dyes and uses for same will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1989067