Method for sequencing nucleic acids

Details Method for sequencing nucleic acids Method for sequencing nucleic acids

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2460329

Method for sequencing nucleic acids in which the values of the CID spectrum calculated for an assumed sequence are compared with the measured spectrum of the nucleic acid and the degree of correspondence is calculated, at least one position of the assumed sequence is modified and the degree of correspondence with the measured spectrum is recalculated.

La présente invention concerne un procédé pour séquencer des acides nucléiques. Selon ce procédé, les valeurs du spectre de dissociation induite par collision (collision induced dissociation : CID), calculées pour une séquence supposée, sont comparées au spectre mesuré de l'acide nucléique et le degré de concordance est calculé, puis au moins une position de la séquence supposée est modifiée et le degré de concordance avec le spectre mesuré est à nouveau calculé

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