Biphenyl derivatives and their use as integrin inhibitors

Details Biphenyl derivatives and their use as integrin inhibitors Biphenyl derivatives and their use as integrin inhibitors

C - Chemistry, Metallurgy

07

D

C07D 235/30 (2006.01) A61K 31/4164 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01) C07D 233/48 (2006.01) C07D 233/88 (2006.01)

Patent

CA 2420208

The invention relates to novel biphenyl derivatives of the general formula (I), wherein R4 represents an aromatic heterocycle, and to the physiologically acceptable salts or solvates thereof. The inventive compounds are integrin inhibitors and are used for combating thromboses, cardiac infarction, coronary heart diseases, arteriosclerosis, inflammations, tumors, osteoporosis, infections and restenosis following angioplasty or for pathological processes that are maintained or propagated by angiogenesis.

Nouveaux dérivés de biphényle de formule générale (I) dans laquelle R?4¿ représente un hétérocycle aromatique, ainsi que les sels ou solvates acceptables sur le plan physiologique desdits dérivés. Lesdits dérivés sont des inhibiteurs d'intégrine et peuvent être utilisés pour lutter contre les thromboses, l'infarctus du myocarde, les cardiopathies coronariennes, les inflammations, les tumeurs, l'ostéoporose, les infections et la resténose après angioplastie ou dans des processus pathologiques qui sont favorisés ou propagés par l'angiogenèse.

Affiliated with

Also associated with

Rating

Biphenyl derivatives and their use as integrin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biphenyl derivatives and their use as integrin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biphenyl derivatives and their use as integrin inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1989654