Ceruloplasmin and uses thereof in neurodegenerative related...

A - Human Necessities – 61 – K

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A61K 38/44 (2006.01) A61K 38/57 (2006.01) A61K 47/48 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2407781

The present invention relates to the use of ceruloplasmin (and/or derivatives thereof) for treating neurodegenerative related conditions. More particularly, the present invention pertains to the use of ceruloplasmin in pharmaceutical neurotrophic compositions, to its use as a carrier for delivering therapeutic agent(s) to tissues of the nervous systems and to its use in methods for culturing neuronal cells in vitro. The present invention is useful for maintaining or stimulating the regeneration of neuronal cells, particularly for the treatment of injuries to the brain, the spinal cord and other central nervous system tissues.

La présente invention concerne l'utilisation de ceruloplasmine (et/ou de ses dérivés) pour traiter des troubles liés à la neurodégénérescence. Plus particulièrement, la présente invention concerne l'utilisation de ceruloplasmine dans des compositions pharmaceutiques neurotrophiques, son utilisation en tant que porteur servant à administrer un/des agent(s) thérapeutique(s) à des tissus du système nerveux, et son utilisation dans des procédés servant à réaliser la culture de cellules neuronales in vitro. La présente invention peut être utilisée pour conserver ou stimuler la régénération de cellules neuronales, en particulier pour le traitement de blessures touchant le cerveau, la moelle épinière, et d'autres tissus du système nerveux central.

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