Stimulus responsive affinity chromatographic material and...

B - Operations – Transporting – 01 – J

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B01J 20/26 (2006.01) B01D 15/08 (2006.01) B01D 15/20 (2006.01) B01D 15/26 (2006.01) B01J 20/285 (2006.01) B01J 20/286 (2006.01) B01J 20/32 (2006.01) G01N 30/54 (2006.01)

Patent

CA 2423589

A separation material characterized by supporting, in its surface, a linear or crosslinked stimulus responsive polymer to which a substance A having specific affinity for a target substance and a low-molecular substance B having specific affinity for the substance A have been bonded. Such a separation material can increase the recovery of a target substance to be purified and do not require desalting and hapten sugar-eliminating operations and, in addition, have high productivity.

L'invention concerne un matériau de séparation caractérisé en ce qu'il supporte, sur sa surface, un polymère linéaire ou réticulé sensible à un stimulus, auquel une substance A ayant une affinité spécifique pour une substance cible et une substance B à bas poids moléculaire ayant une affinité spécifique pour la substance A ont été liées. Un tel matériau de séparation peut permettre une guérison améliorée d'une substance cible à purifier, ne nécessite pas d'opérations de dessalage et d'élimination de sucre d'un haptène, et, de plus, permet d'obtenir une productivité élevée.

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