Drug combination for the treatment of headache comprising...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/55 (2006.01) A61K 31/165 (2006.01) A61K 31/19 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2404358

The invention relates to a combination comprising paracetamol or a non- steroidal anti-inflammatory drug (NSAID), or a pharmaceutically acceptable salt or solvate thereof, and another drug, in which combination the other drug is mirtazapine, or a pharmaceutically acceptable salt or solvate thereof, optionally in association with one or more pharmaceutically acceptable carriers, whereby paracetamol or an NSAID and mirtazapine are present in the combination in such amounts that the effect of the composition is more favourable than the added effects of the amounts of each drug separately. This combination can be used in the treatment of headache, whereby the invention also provides for a new method of treatment of headache.

L'invention concerne une combinaison comprenant du paracétamol ou un médicament anti-inflammatoire non stéroïde (NSAID) ou leur solvate ou sel pharmaceutiquement acceptable ainsi qu'un autre médicament; dans cette combinaison, l'autre médicament est la mirtazapine ou son solvate ou sel pharmaceutiquement acceptable, éventuellement en association avec un ou plusieurs excipients pharmaceutiquement acceptables. Le paracétamol, le NSAID et la mirtazapine sont présents dans la combinaison dans des quantités telles que l'effet de la composition est plus favorable que les effets cumulés des doses séparées de chaque médicament. Cette combinaison peut s'utiliser dans le traitement du mal de tête; l'invention concerne aussi un nouveau procédé de traitement du mal de tête.

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