C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 303/48 (2006.01) C07C 319/14 (2006.01) C07C 323/56 (2006.01) C07D 213/70 (2006.01) C07D 233/84 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01) C07D 407/10 (2006.01) C07D 409/10 (2006.01)
Patent
CA 2088355
2088355 9202519 PCTABS00010 This invention relates to intermediate compounds of formula (VI), wherein: R1 is (L)a-(CH2)b-(T)c-B; a is 0 or 1; b is 3 to 14; c is 0 or 1; L and T are independently sulfur, oxygen, CH=CH, C=C, or CH2; B is H, C1-4alkyl, ethynyl, trifluoromethyl, isopropenyl, furanyl, thienyl, cyclohexyl or phenyl unsubstituted or monosubstituted by Br, Cl, CF3, C1-4alkoxy, C1-4alkyl, methylthio or trifluoromethylthio; R2 and A are independently selected from H, CF3, C1-4alkyl, C1-4alkoxy, F, Cl, Br, I, OH, NO2 or NH2; or, when R1 and A are H, R2 is (L)a-(CH2)b-(T)c-B wherein a, b, c, L, T and B are as defined above; and M is H, Li, Na, K, NH4 or an organic ammonium cation, and their use in a process for preparing leukotriene antagonists.
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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