Derivatives of n-[(4,5-diphenyl-3-alkyl-2-thienyl) methyl]...

Details Derivatives of n-[(4,5-diphenyl-3-alkyl-2-thienyl) methyl]... Derivatives of n-[(4,5-diphenyl-3-alkyl-2-thienyl) methyl]...

C - Chemistry, Metallurgy

07

D

C07D 333/20 (2006.01) A61K 31/381 (2006.01) A61P 1/00 (2006.01) A61P 3/04 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) A61P 25/30 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2596613

The invention relates to compounds of formula (I) wherein X represents a group of formula (II); and R3 and R4 independently represent a non-substituted, monosubstituted, disubstituted, or trisubstituted phenyl. The invention also relates to a method for the preparation and application of said compounds as cannabinoid CB1 receptor antagonists.

La présente invention a pour objet des composés répondant à la formule (I) dans laquelle : - X représente un groupe formule (II); - R3 représente un phényle non substitué ou mono-, di- ou trisubstitué ; - R4 représente un phényle non substitué ou mono-, di- ou trisubstitué ; Procédé de préparation et application comme antagonistes des récepteurs CB1 des cannabinoides.

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