C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2542171
This invention relates to drug screening using mammalian repulsive guidance molecules and mammalian Neogenin. In addition, the invention provides for methods of preventing, alleviating or treating various disorders of the nervous system, angiogenic disorders or disorders of the cardio-vascular system and malignancies of different etiology by disrupting the interaction between RGM and Neogenin.
L'invention se rapporte au criblage de médicaments au moyen de molécules de guidage répulsives mammaliennes et de néogénine mammalienne. En outre l'invention se rapporte à des méthodes visant à prévenir, soulager ou traiter divers troubles du système nerveux, des troubles angiogéniques ou des troubles du système cardio-vasculaire ainsi que des tumeurs malignes d'étiologie différentes au moyen d'une perturbation de l'interaction entre les molécules de guidage répulsives (RGM) et la néogénine.
Deitinghoff Lutz
Mueller Bernhard
Strittmatter Stephen
Abbott Gmbh & Co. Kg
Deitinghoff Lutz
Mbm Intellectual Property Law Llp
Mueller Bernhard
Strittmatter Stephen
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