Carboxymethylgalactose derivatives

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 15/04 (2006.01) A61K 31/70 (2006.01) A61K 31/7028 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07H 15/10 (2006.01)

Patent

CA 2344652

Carboxymethylgalactose derivatives represented by general formula (1); Image and salts thereof, which exhibit reactivity to selectins and are useful as inhibitors against selectin-related diseases such as various inflammations and cancerous metastasis; In said formula, R is a group represented by formula (1a), (1b) or (1c). Image

Cette invention se rapporte à des dérivés de carboxyméthylgalactose, représentés par la formule générale (1); ou à des sels de ces dérivés, qui possèdent une réactivité aux sélectines et qui sont utiles comme inhibiteurs contre les maladies liées aux sélectines, telles que diverses inflammations et les métastases cancéreuses. Dans la formule (1), R est un groupe représenté par la formule (1a), (1b) ou (1c).

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