Use of stabilised oligonucleotides for preparing a medicine...

Details Use of stabilised oligonucleotides for preparing a medicine... Use of stabilised oligonucleotides for preparing a medicine...

A - Human Necessities

61

K

A61K 31/711 (2006.01) A61K 31/7115 (2006.01) A61K 31/7125 (2006.01) A61K 31/713 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2371990

The invention concerns the use of stabilised oligonucleotides comprising at least an octamer motif of the type: 5'-purine-purine-CG-pyrimidine-pyrimidine-X¿1?X¿2?-3' wherein the pair X¿1?-X¿2? is AT, AA, CT or TT, for preparing a medicine with antitumour activity.

Utilisation d'oligonucléotides stabilisés qui comprennent au moins un motif octamérique du type: 5'-purine-purine-CG-pyrimidine-pyrimidine-X¿1?X¿2?-3', dans lequel la paire X¿1?-X¿2? est AT, AA, CT ou TT, pour la préparation d'un médicament à action antitumorale.

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