A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/519 (2006.01) A61K 31/4985 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2575821
The invention relates to aqueous infusion or injection solutions that have a long shelf life and contain an active substance of general formula (I), wherein the radicals L, R1, R2, R3, R4, and R5 have the meanings indicated in the claims and the description, an amount of a physiologically acceptable acid or acid mixture which is sufficient to dissolve the active substance and stabilize the solutions, and additional optional auxiliary formulation agents suitable for parenteral use. Also disclosed is a method for producing the inventive infusion or injection solutions.
La présente invention concerne des solutions aqueuses de perfusion ou d'injection contenant un principe actif de la formule générale (I) où les restes L, R1, R2, R3, R4 et R5 ont la signification donnée dans les revendications et la description, et une quantité suffisante d'un acide ou d'un mélange acide physiologiquement compatible aux fins de dissolution du principe actif ou de stabilisation, et éventuellement d'autres adjuvants de formulation adaptés à l'application parentérale. L'invention concerne enfin un procédé de production des solutions de perfusion ou d'injection selon l'invention.
Mohr Detlef
Traulsen Fridtjof
Veit Claus
LandOfFree
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