Therapeutic application of an anti-invasion compound

A - Human Necessities – 61 – K

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A61K 31/41 (2006.01) A61K 31/4192 (2006.01)

Patent

CA 2057021

2057021 9014009 PCTABS00002 Tumor invasion and metastasis is the most life threatening aspect of cancer. Invasion and metastasis is a multistep process. Cellular functions required for invasion are attachment, locomotion and directed migration. Regulation of these processes may be independent of cell growth. A carboxyl-amino-imidazole compound was found to be a potent inhibitor of tumor cell attachment, motility, invasion, proliferation, and metastasis. This compound and equivalents thereof consistute a cancer treatment agent of particular use in the treatment of peritoneal carcinomatosis of ovarian cancer.

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