Vaccine comprising antigens bound to carriers through labile...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 39/385 (2006.01) A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61K 39/23 (2006.01) C07K 7/23 (2006.01) C07K 14/015 (2006.01)

Patent

CA 2260761

The invention is in the field of vaccines and immunogenic preparations. Normally in these preparations antigens and carrier compounds are irreversibly coupled in a stable bond. The invention, to the contrary, provides vaccines and immunogenic preparations in which the antigen (be it protein or peptide or carbohydrate or any other molecule to be used as an antigen for immunization/vaccination procedures) and the carrier compound are coupled in a reversible and labile way, with a so-called labile link. In this way, as is demonstrated in the experimental part of this application, surprisingly a better immune response can be elicited by an in itself poorly immunogenic antigen than by methods that provide a stable link between the antigen and carrier compound.

L'invention se situe dans le domaine des vaccins et des préparations immunogènes. Normalement, dans ces préparations, les antigènes et les composés supports sont irréversiblement couplés par une liaison stable. L'invention, au contraire, concerne des vaccins et des préparations immunogènes dans lesquels l'antigène (qu'il soit une protéine, un peptide, un hydrate de carbone ou n'importe quelle autre molécule pouvant être utilisée comme antigène en vue d'une immunisation/vaccination) et le composé support sont couplés de manière réversible et labile, par ce qu'on appelle une liaison labile. Etonnamment, comme cela a été démontré dans la partie expérimentale de cette demande, un antigène faiblement immunogène par lui-même peut ainsi provoquer une meilleure réponse qu'avec les méthodes dans lesquelles l'antigène et le composé support sont liés par une liaison stable.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Vaccine comprising antigens bound to carriers through labile... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Vaccine comprising antigens bound to carriers through labile..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vaccine comprising antigens bound to carriers through labile... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2000498

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.