Compositions with reduced hepatotoxicity

Details Compositions with reduced hepatotoxicity Compositions with reduced hepatotoxicity

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/16 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2561619

Pharmaceutical compositions of hepatotoxic compounds are provided in which the hepatotoxicity of the compounds is mitigated by including quantities of nicotinamide and methionine in the composition. Folic acid also can be included to further mitigate the hepatotoxic effects. The hepatotoxic compounds can include acetaminophen, methotrexate, atorvastatin, simvastatin, niacin, flucanozole, divalproex sodium, and valproic acid.

L'invention concerne des compositions pharmaceutiques de composés hépatotoxiques dans lesquelles l'hépatotoxicité est limitée par adjonction de quantités de nicotinamide et de méthionine dans ladite composition. On peut également ajouter un acide folique afin de limiter les effets hépatotoxiques. Lesdits composés hépatotoxiques peuvent comprendre un acétaminophène, un méthotrexate, une atorvastatine, une simvastatine, une niacine, un flucanozole, un divalproex sodique, et un acide valproïque.

Affiliated with

Also associated with

Rating

Compositions with reduced hepatotoxicity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions with reduced hepatotoxicity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions with reduced hepatotoxicity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2001032