Composition for controlled release of an active substance...

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/36 (2006.01) A61K 9/20 (2006.01) A61K 9/26 (2006.01)

Patent

CA 2139493

The invention provides a composition for delayed release of an active substance, the active substance being incorporated in a polysaccharide matrix which consists of an essentially crystalline straight-chain glucan and contains a glucan-degrading agent. The glucan is in particular an .alpha.-glucan which has essentially a helix structure. The glucan-degrading agent is preferably .alpha.-amy- lase. The composition can contain high-molecular materials such as proteins, allergens, vaccine substance and microorganism, and preferably has the form of compressed tablets.

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