Preventives/remedies for multiple organ failure

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/00 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 38/57 (2006.01) C07D 207/00 (2006.01) C07D 207/12 (2006.01) C07D 209/00 (2006.01) C07D 211/00 (2006.01) C07D 211/46 (2006.01) C07D 333/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2342796

Preventives/remedies for syndrome caused by the worsening of sepsis, hyperchemokinemia and hepatic diseases which contain as the active ingredient an antithrombin agent and/or a thrombin synthesis inhibitor. Because of being usable in preventing or treating diseases including sepsis, severe sepsis, septic shock and multiorgan failure, these drugs are useful in the treatment of trauma, burn, heat attack, severe infection, etc. caused by, in particular, traffic accidents in the field of emergency care. These drugs are also useful in preventing and treating hyperchemokinemia and hepatic diseases.

L'invention concerne des médicaments préventifs/et des remèdes contre la défaillance de plusieurs organes provoquée par l'aggravation de la septicémie, de l'hyperchémokinémie et des maladies hépatiques, contenant un agent antithrombine et/ou un inhibiteur de synthèse de la thrombine utilisé comme agent actif. Du fait qu'on peut les utiliser dans la prévention ou le traitement de maladies telles que la septicémie, la septicémie sévère, un choc septique et la défaillance de plusieurs organes, ces médicaments sont utiles pour traiter un traumatisme, une brûlure, un malaise dû à la chaleur, une infection sévère, etc., provoqués en particulier par les accidents de la route, en cas de soins d'urgence. Ces médicaments sont également utiles pour prévenir et traiter l'hyperchémokinémie et les maladies hépatiques.

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