System of analyzing complex mixtures of biological and other...

G - Physics – 01 – N

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G01N 33/68 (2006.01) A61B 5/00 (2006.01) G01N 30/72 (2006.01) G01N 33/48 (2006.01) H01J 49/04 (2006.01)

Patent

CA 2467144

A business method for use in classifying patient samples. The method includes steps of collecting case samples representing a clinical phenotypic state and control samples representing patients without said clinical phenotypic state. Preferably the system uses a mass spectrometry platform system to identify patterns of polypeptides in said case samples and in the control samples without regard to the specific identity of at least some of said polypeptides. Based on identified representative patterns of the state, the system performs optimized assays for greater sensitivity, specificity, and/or cost effectiveness and the business method provides for the marketing of diagnostic products using representative patterns.

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