C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4525 (2006.01) A61K 31/4535 (2006.01) A61K 31/454 (2006.01) A61K 31/506 (2006.01) A61P 25/00 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2687321
The present invention is. directed to pyridyl piperidine compounds of formula (I) which are antagonists of orexin receptors, and which are useful' in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
La présente invention concerne des composés pyridyl pipéridine de formule (I) qui sont des antagonistes de récepteur d'orexine, et qui sont utiles dans le traitement ou la prévention de troubles et maladies neurologiques et psychiatriques dans lesquels les récepteurs d'orexine sont impliqués. L'invention concerne des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés et compositions dans la prévention et le traitement de telles maladies dans lesquelles des récepteurs d'orexine sont impliqués.
Breslin Michael J.
Coleman Paul J.
Cox Christopher D.
Schreier John D.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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