Epoxide hydrolases, nucleic acids encoding them and methods...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/55 (2006.01) A01H 5/00 (2006.01) A01H 5/10 (2006.01) A01K 67/02 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 16/40 (2006.01) C07K 17/00 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 5/12 (2006.01) C12N 9/14 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12N 15/67 (2006.01) C12P 7/02 (2006.01) C12P 7/18 (2006.01) C12P 17/02 (2006.01) C12P 17/04 (2006.01) C12P 17/12 (2006.01) C12P 17/16 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2

Patent

CA 2456229

The invention is directed to polypeptides having epoxide hydrolase activity, polynucleotides encoding the polypeptides, antibodies that bind to these polypeptides, and methods for making and using these polynucleotides and polypeptides. The epoxide hydrolases are used to catalyze the hydrolysis of epoxides and arene oxides to their corresponding diols.

La présente invention se rapporte à des polypeptides présentant une activité d'époxyde-hydrolase, à des polynucléotides codant ces polypeptides, à des anticorps qui se lient à ces polypeptides ainsi qu'à des procédés de fabrication et d'utilisation de ces polynucléotides et polypeptides. Ces époxydes-hydrolases sont utilisés pour catalyser l'hydrolyse des époxydes et des arènes oxydes en leurs diols correspondants.

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