A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01)
Patent
CA 2594065
The invention relates to a transdermal therapeutic system (TTS) that is essentially composed of two compartments and that is provided with activatable oversaturation and controlled permeation promotion. The invention more particularly relates to a TTS, wherein an oversaturated active ingredient solution is produced in an active-substance-containing polymer matrix when the system is applied to the skin, caused by the controlled supply of one or several substances promoting permeation of the pharmaceutical active ingredient; the two compartments which make up the inventive transdermal therapeutic system; and the production of said transdermal therapeutic system from the two compartments.
La présente invention concerne un système thérapeutique transdermique (TTS) à sursaturation activable et pénétration contrôlée, qui se compose principalement de deux compartiments. L'invention concerne en particulier un TTS avec lequel une solution de principe actif sursaturée est produite dans la matrice polymère contenant le principe actif, uniquement à l'application du système sur la peau, grâce à l'apport contrôlé d'une ou de plusieurs substances qui permettent la pénétration du principe actif pharmaceutique. L'invention a également pour objet les deux compartiments qui composent le système thérapeutique transdermique de l'invention, ainsi que la réalisation de ce système thérapeutique transdermique à partir des deux compartiments.
Blake Cassels & Graydon Llp
Lts Lohmann Therapie-Systeme Ag
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