Apparatus and method for streaming electroporation

A - Human Necessities – 61 – N

Patent

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A61N 1/30 (2006.01) A61N 1/32 (2006.01) C12M 1/42 (2006.01) C12M 3/00 (2006.01) C12N 13/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2497649

Techniques for streaming electroporation. A representative but non-limiting method includes: generating a spatially inhomogeneous electric field with a pair of electrodes and displacing the pair of electrodes and a sample relative to one other while the electric field is substantially constant in terms of magnitude so that the sample is displaced across electric field lines for a time sufficient to effect electroporation.

La présente invention concerne des techniques permettant de réaliser de façon non statique une électroporation. L'un des procédés retenus consiste à produire un champ électrique spatialement non homogène à partir d'une paire d'électrodes et à déplacer la paire d'électrodes et un échantillon l'un par rapport à l'autre, le champ électrique restant de grandeur sensiblement constante, de façon que l'échantillon coupe l'ensemble des lignes de champ électrique assez longtemps pour réaliser l'électroporation.

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