Apparatus and methods for the automated synthesis of...

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B01J 19/00 (2006.01) C07B 61/00 (2006.01) C07H 15/10 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2420183

One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on solid-phase particles. In certain embodiments, the apparatus of the present invention is used in combinatorial methods, e.g., as described herein, of synthesizing oligosaccharides.

Dans un aspect, l'invention concerne un dispositif permettant de synthétiser efficacement des oligosaccharides sur un support solide, p. ex. par addition de sous-unités aux sous-unités terminales immobilisées sur des particules en phase solide. Dans certaines formes de réalisation, ce dispositif est utilisé pour la mise en oeuvre de processus combinatoires, p. ex. pour la synthèse d'oligosaccharides telle qu'elle est décrite dans la présente invention.

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