Tetrazole derivatives and drugs

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 257/04 (2006.01) A61K 31/41 (2006.01) A61K 31/47 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2086117

ABSTRACT The invent1on relates to a compound of the following general formula [I] or a pharmacologically acceptable salt thereof. Image [ I ] [wherein A means -(O)m-(CH(R4))n- (R4 is hydrogen or alkyl; m and n each is 0 or 1); B means oxygen or -S(O)p- (p is 0 to 2) ; R' means hydrogen, lower alkyl, lower alkoxy, halogen, haloalkyl or hydroxy; R2 means alkyl, alkenyl or aralkyl, which may be substituted or unsubstituted; R9 means hydrogen, lower alkoxy or halogen; R9 means hydrogen, lower alkyl, lower alkoxy, lower acyloxy, halogen, nitro or hydroxy; R10 means hydrogen or lower alkyl]. This compound has antiallergy and antiinflammatory activities and is of use as a therapeutic agent for bronchial asthma, allergic rhinitis and so on.

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