Process for the preparation of a non-crystalline anhydrate...

Details Process for the preparation of a non-crystalline anhydrate... Process for the preparation of a non-crystalline anhydrate...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01)

Patent

CA 2339857

Paroxetine hydrochloride propan-2-ol solvate is desolvated to remove propan-2- ol and prepare paroxetine hydrochloride anhydrate by heating the solvate mass and increasing the temperature of the heating as the amount of propan-2-ol remaining in the solvate mass decreases.

L'invention concerne procédé consistant à désolvater un solvate de d'hydrochlorure de paroxétine et de 2-propanol et à préparer un hydrochlorure de paroxétine anhydre en chauffant la masse de solvate et en augmentant la température à mesure que la quantité de 2-propanol restant dans la masse de solvate diminue.

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