A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2732715
It is an object of the present invention to provide a treatment agent and a preventive agent for osteoarthritis and arthritis (arthromeningitis) derived from osteoarthritis. [Means for solving problem(s)] The present invention is based on a knowledge that the use of an anti-Fas IgM antibody allows the alleviation of an osteoarthritis symptom. Specifically, the present invention is based on a knowledge that the use of an anti-Fas IgM antibody allows the inhibition of production of a cartilage matrix degrading enzyme. Furthermore, the present invention is based on a knowledge that the use of an anti-Fas IgM antibody can improve the ability to produce a cartilage matrix.
La présente invention concerne un agent thérapeutique et un agent préventif pour l'arthrose et l'inflammation arthrosique (synovite). L'invention est fondée sur la découverte que les symptômes de l'arthrose peuvent être soulagés à l'aide d'un anticorps anti-Fas de type IgM. L'invention est fondée plus précisément sur la découverte que la production d'une enzyme de dégradation de la matrice cartilagineuse peut être inhibée à l'aide d'un anticorps anti-Fas de type IgM. L'invention est également fondée sur la découverte que la productivité de la matrice cartilagineuse peut être améliorée à l'aide d'un anticorps anti-Fas de type IgM.
Nishioka Kusuki
Yudo Kazuo
Axis Inc.
Borden Ladner Gervais Llp
Mpo Inc.
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