Phenoxyphenyl alkane sulfonates

Details Phenoxyphenyl alkane sulfonates Phenoxyphenyl alkane sulfonates

C - Chemistry, Metallurgy

07

C

C07C 309/65 (2006.01) A61K 31/18 (2006.01) A61K 31/255 (2006.01) A61P 25/28 (2006.01) C07C 311/08 (2006.01) C07C 311/09 (2006.01)

Patent

CA 2423171

The invention relates to phenoxyphenyl alkane sulfonates of the formula (I), wherein A represents oxygen or NH, and R3 represents (C4-C7) alkyl that can be mono- or polysubstituted by fluorine or chlorine. The invention further relates to methods for producing the same, to the use of said sulfonates in the production of medicaments for the treatment and/or the prophylaxis of diseases, especially for treating pain conditions and neurodegenerative diseases.

La présente invention concerne des sulfonates d'alcane de phénoxyphényle de formule (I), dans laquelle A représente oxygène ou NH et R?3¿ représente alkyle (C¿4?-C¿7?) pouvant être substitué une fois ou plusieurs fois par fluor ou par chlore. La présente invention concerne également le procédé de production de ces composés, ainsi que leur utilisation dans la production de médicaments destinés au traitement et/ou à la prophylaxie de maladies, notamment au traitement d'états douloureux et de maladies neurodégénératives.

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