Cycloalkyl-substituted alkanoic acid derivatives, methods...

C - Chemistry – Metallurgy – 07 – C

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C07C 275/26 (2006.01) A61K 31/17 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07C 275/10 (2006.01) C07C 275/24 (2006.01) C07C 275/28 (2006.01) C07D 309/00 (2006.01) C07D 319/00 (2006.01) C07D 323/04 (2006.01) C07D 325/00 (2006.01)

Patent

CA 2516633

The invention relates to arlylcycloalkyl-substituted alkanoic acid derivatives and the physiologically acceptable salts and physiologically functional derivatives thereof. Disclosed are compounds of formula (I), wherein the radicals have the indicated meanings, the physiologically acceptable salts thereof, and methods for the production thereof. Said compounds are suitable for treating and/or preventing disturbances of fatty acid metabolism, impaired glucose utilization, and disturbances in which insulin resistance plays a role.

La présente invention concerne des dérivés d'acide alcanoïque à substitution arylcycloalkyle, ainsi que des sels de ceux-ci, compatibles d'un point de vue physiologique, et des dérivés de ceux-ci, fonctionnels d'un point de vue physiologique. Il s'agit de composés de formule (I), dans laquelle les radicaux ont les significations données, ainsi que de leurs sels, compatibles d'un point de vue physiologique, et de procédés pour les produire. Ces composés sont utilisés pour traiter et/ou prévenir des troubles du métabolisme des acides gras et des troubles de l'utilisation de glucose, ainsi que des troubles avec lesquels une résistance à l'insuline joue un rôle.

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