Genetically-modified fibroblasts and the use thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/10 (2006.01) C07K 14/47 (2006.01) C12N 5/06 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2331826

A method for the preparation of genetically-modified fibroblasts expressing a muscle lineage commitment gene, and the use thereof for the treatment of genetic defects or for the expression of therapeutic proteins.

L'invention concerne un procédé relatif à l'élaboration de fibroblastes génétiquement modifiés exprimant un gène de détermination de lignée musculaire, et elle concerne aussi l'utilisation de ces fibroblastes pour le traitement des défauts génétiques ou pour l'expression de protéines thérapeutiques.

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